What is Angilock Plus 50/12.5mg?
Angilock Plus 50/12.5mg Tablets is a combination medicine used primarily for the treatment of hypertension (high blood pressure). Each tablet contains losartan potassium 50 mg and hydrochlorothiazide 12.5 mg.
The medicine combines two antihypertensive agents with complementary actions. Losartan belongs to a class called angiotensin II receptor blockers (ARBs), while hydrochlorothiazide is a thiazide diuretic.
How does Angilock Plus work?
Losartan blocks the action of angiotensin II, a hormone that causes blood vessels to narrow. By blocking angiotensin II at its receptors, losartan allows blood vessels to relax and widen, helping lower blood pressure.
Hydrochlorothiazide increases the amount of sodium and water eliminated by the kidneys. This reduces excess fluid in the body and contributes to lowering blood pressure.
Together, these two medicines help control blood pressure through complementary mechanisms.
What is Angilock Plus used for?
Angilock Plus is primarily used to treat essential hypertension, commonly known as high blood pressure.
Controlling high blood pressure is important because persistently elevated blood pressure increases the risk of cardiovascular and kidney complications.
PRECAUTIONS & WARNINGS
- Prescription medicine — use under medical supervision.
- Do not use if allergic to losartan, hydrochlorothiazide or any ingredient in the medicine.
- Do not use during pregnancy. Contact a healthcare professional immediately if pregnancy occurs.
- Tell your doctor if you have kidney or liver disease.
- Tell your doctor if you have previously experienced electrolyte abnormalities.
- Do not use potassium supplements or potassium-containing salt substitutes without medical advice.
- Inform your healthcare professional about all other medicines you take.
- NSAIDs such as ibuprofen or diclofenac may affect blood-pressure control and kidney function and should be discussed with your healthcare professional.
- Monitor blood pressure regularly.
- Avoid excessive dehydration, particularly during illness, vomiting or diarrhoea.
- Hydrochlorothiazide may increase sensitivity to sunlight; protect exposed skin from excessive sun exposure.
COMMON SIDE EFFECTS
Possible side effects include:
- Dizziness
- Headache
- Increased urination
- Fatigue
- Nausea
- Changes in electrolyte levels
- Low blood pressure
Seek urgent medical attention for severe allergic reactions, difficulty breathing, fainting, severe weakness, significant reduction in urine output or other serious or unusual symptoms.











