Product Overview
Hydrocortisone Injection is a corticosteroid medicine used in hospital and clinical settings to manage certain severe inflammatory or allergic conditions and adrenal insufficiency. Injectable hydrocortisone is commonly supplied as hydrocortisone sodium succinate powder that is reconstituted before administration.
How It Works
Hydrocortisone binds to glucocorticoid receptors inside cells and changes the expression of genes involved in inflammation and immune responses. This reduces the production of inflammatory mediators, helping control swelling, redness and excessive immune activity. It also has glucocorticoid and mineralocorticoid effects that help replace cortisol and support blood pressure and fluid balance in patients with adrenal insufficiency.
Uses and Indications
Acute adrenal insufficiency
Severe allergic or inflammatory conditions
Selected severe asthma exacerbations
Certain autoimmune and rheumatic conditions
Precautions and Warnings
May increase blood glucose and blood pressure.
Can worsen or mask certain infections.
Use cautiously in people with diabetes, hypertension, heart failure or stomach ulcers.
Repeated or prolonged use can cause additional corticosteroid-related effects.
Confirm the strength and route from the vial before use.
Common Side Effects
Increased blood glucose
Fluid retention
Increased blood pressure
Stomach discomfort
Mood changes
Increased susceptibility to infection
