OVERVIEW
Ciprofloxacin 500mg Tablets 10's contain ciprofloxacin, an antibiotic belonging to the fluoroquinolone class. It works against certain bacteria and is prescribed for specific infections when the medicine is considered appropriate based on the infection, likely bacterial susceptibility and the patient's medical history.
Mechanism of Action: How It Works
Ciprofloxacin inhibits two bacterial enzymes: DNA gyrase and topoisomerase IV. These enzymes are essential for bacterial DNA replication and repair. By disrupting their activity, ciprofloxacin prevents susceptible bacteria from multiplying and can kill them.
Uses and Indications
Ciprofloxacin may be prescribed for certain bacterial infections, including:
Selected urinary tract and kidney infections.
Certain gastrointestinal infections.
Selected skin, soft-tissue, bone and joint infections.
Certain genital tract infections.
Specific respiratory infections when ciprofloxacin is considered appropriate.
Precautions and Warnings
Tendon injury: Ciprofloxacin can cause tendon inflammation or rupture. Stop taking it and seek prompt medical advice if tendon pain or swelling develops.
Nerve problems: Stop and seek medical advice for new burning, tingling, numbness or weakness.
Nervous system effects: Serious effects can include seizures and changes in mood, behaviour or mental state.
Drug interactions: Ciprofloxacin interacts with several medicines. It must not be taken with tizanidine. Tell your healthcare professional about all medicines and supplements you use.
Kidney impairment: Dose adjustment may be necessary.
Pregnancy and breastfeeding: Seek professional advice before use.
Children and adolescents: Use is restricted to specific indications under specialist supervision.
Antibiotic resistance: Do not use without a prescription or for viral infections.
Common Side Effects
Possible side effects include:
Nausea.
Diarrhoea.
Abdominal discomfort.
Headache.
Dizziness.
Sleep disturbances.
Serious reactions can also occur, including severe allergic reactions, tendon damage, peripheral neuropathy and significant mental or neurological effects. Seek urgent medical attention for severe symptoms, and promptly report tendon pain, swelling, numbness or tingling.
